Clinical impact of rehabilitation and <scp>ICU</scp> diary on critically ill patients: A systematic review and meta‐analysis

Background Various physical and mental sequelae reduce the quality of life (QOL) intensive care unit (ICU) patients. Current guidelines recommend multi-angular approaches to prevent these sequelae. Some studies have demonstrated clinical effectiveness rehabilitation or ICU diary against sequelae, whereas others not. Aim The aims present study were establish whether was useful for reducing severity anxiety, depression, post-traumatic stress disorder (PTSD) in We also investigated interventions improved QOL Study design conducted a systematic review meta-analysis relevant randomized controlled trials published between January 1, 1985, October 19, 2022, with following search engines: PubMed, CHINAHL, all Ovid journals, CENTRAL. hospital anxiety depression scale (HADS), short-form health survey (SF-36), EuroQol 5-dimensions, 5-levels (EQ-5D-5L), Impact Event Scale-Revised (IES-R) used as outcome measures. evidence across independently assessed using Review Manager software (v.5.4). Results included 12 five studies. Rehabilitation had no significant effects on HADS-anxiety, HADS-depression, EQ-5D-5L, but significantly component summary (PCS) [MD = 3.31, 95%CI (1.33 5.28), p .001] (MCS) 4.31, 95%CI: (1.48 7.14), .003] SF-36. ameliorated HADS-anxiety 0.96, (0.21 1.71), .01], did not affect IES-R, PCS MCS Conclusions showed that initiated after discharge from effectively SF-36 scores. HADS-anxiety. Neither nor attenuated HADS-depression IES-R this setting. partially long-term prognosis Relevance practice provides beneficial alone does ameliorate PTSD symptoms, may improve QOL. only appeared anxiety.